Patients suffering from fibromyalgia were hopeful that low-dose naltrexone, an opioid receptor antagonist, would provide them with much-needed pain relief. However, a recent randomized trial dashed those hopes. According to Dr. Karin Due Bruun and colleagues from Odense University Hospital in Denmark, the trial showed that patients assigned to naltrexone experienced a mean decline in
Health
In a recent study presented at the International Gynecologic Cancer Society’s annual meeting, trastuzumab deruxtecan (T-DXd), an antibody-drug conjugate, demonstrated highly encouraging response rates in patients with HER2-expressing gynecologic cancers. Dr. Ritu Salani of the University of California Los Angeles discusses the findings from the DESTINY-PanTumor02 trial and explains why they have the potential to
In a groundbreaking study known as the RAFT trial, researchers have made significant progress in the treatment of fetal renal agenesis, a condition that has previously been uniformly lethal. Serial infusions of amniotic fluid were used to restore lost amniotic fluid due to the lack of fetal renal development before 26 weeks’ gestation. The results
The randomized IMerge trial has shown that patients with lower-risk myelodysplastic syndromes (MDS) who relapsed or were refractory to standard treatment achieved improved rates of red blood cell (RBC) transfusion independence with an investigational telomerase inhibitor called imetelstat. This first-in-class drug demonstrated significantly higher rates of RBC transfusion independence for at least 8 weeks compared
When your carefully planned path is suddenly derailed by a devastating diagnosis, the weight of uncertainty can be suffocating. As a young medical student thrust into the world of cancer, I found myself grappling with questions I never anticipated. How would this impact my relationships? Could I still achieve my dreams? Would the medical bills
The highly publicized “Take Care of Maya” trial concluded recently with a staggering $261 million verdict in compensatory and punitive damages for the Kowalski family. The jury held Johns Hopkins All Children’s Hospital of Florida responsible for various claims, including Beata Kowalski’s wrongful death by suicide, infliction of emotional distress, and false imprisonment and battery.
Atopic dermatitis, a chronic inflammatory skin condition, has long lagged behind psoriasis in terms of treatment options. However, recent developments in the field have sparked excitement among dermatologists. In this article, we will discuss the emergence of new and upcoming treatments for atopic dermatitis patients, with a particular focus on the differences in the mechanism
Children under the age of 5 who are infected with HIV and receive antiretroviral treatment (ART) face alarming mortality rates, according to a recent study conducted by the CDC. The study, led by Dr. Nickolas Agathis and his colleagues at the CDC’s Global Health Center in Atlanta, revealed that globally, children under the age of
Headaches are a common ailment that affects millions of individuals worldwide. The exact causes of headaches, especially tension-type and migraine headaches, have remained largely unknown. However, a recent prospective cohort study conducted at University Hospital Ulm in Germany suggests that inflammation and edema of the trapezius muscles may be linked to these types of headaches.
The investigational bispecific antibody ubamatamab (REGN4018) has shown potential in the treatment of recurrent ovarian cancer, according to a phase I study presented at the International Gynecologic Cancer Society (IGCS) annual meeting. Dr. Roisin O’Cearbhaill from Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College shared updated results of the study, highlighting the safety